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In-silico Truth and Beauty of Biological Systems : An Engineer's Perspective

Petros Koumoutsakos

Chair of Computational Science, ETH-Zurich, Caltech Visitor in E&AS

2:00PM - 3:00PM

December 10, 2009 (Thursday)

Broad 100

I will discuss an engineer’s perspective in the formulation of in silico models for bilological systems. The discussion will be based on a number of biological problems including FRAP simulations in an image reconstructed Endoplasmic Reticulum, tumor induced angiogenesis and the reverse engineering of stochastic models for in-vivo virus transport on microtubules.

The simulations of these systems will be in turn analysed in terms of validation possibilities and computational requirements.

I will argue no more than that truth and beauty are two empowering principles that are common in disciplines such as engineering and biology.